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  1. Content type: Research article

    The aim was to review the literature to identify the most effective methods for creating a representative sample of refugee and asylum seeker groups living in the community to participate in health and mental ...

    Authors: Joanne C. Enticott, Frances Shawyer, Shiva Vasi, Kimberly Buck, I-Hao Cheng, Grant Russell, Ritsuko Kakuma, Harry Minas and Graham Meadows

    Citation: BMC Medical Research Methodology 2017 17:37

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  2. Content type: Research article

    The development of Electronic Health Records (EHRs) in hospitals offers the ability to reuse data from patient care activities for clinical research. EHR4CR is a European public-private partnership aiming to d...

    Authors: Yannick Girardeau, Justin Doods, Eric Zapletal, Gilles Chatellier, Christel Daniel, Anita Burgun, Martin Dugas and Bastien Rance

    Citation: BMC Medical Research Methodology 2017 17:36

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  3. Content type: Research article

    The most rigorous method for evaluating the effectiveness of diagnostic tests is through randomised trials that compare test-treatment interventions: complex interventions comprising episodes of testing, decis...

    Authors: Lavinia Ferrante di Ruffano, Jacqueline Dinnes, Sian Taylor-Phillips, Clare Davenport, Chris Hyde and Jonathan J. Deeks

    Citation: BMC Medical Research Methodology 2017 17:32

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  4. Content type: Research article

    There is a growing recognition for the need to expand our evidence base for the clinical effectiveness of diagnostic tests. Many international bodies are calling for diagnostic randomized controlled trials to ...

    Authors: Lavinia Ferrante di Ruffano, Jacqueline Dinnes, Alice J. Sitch, Chris Hyde and Jonathan J. Deeks

    Citation: BMC Medical Research Methodology 2017 17:35

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  5. Content type: Research Article

    When developing risk models for binary data with small or sparse data sets, the standard maximum likelihood estimation (MLE) based logistic regression faces several problems including biased or infinite estima...

    Authors: M. Shafiqur Rahman and Mahbuba Sultana

    Citation: BMC Medical Research Methodology 2017 17:33

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  6. Content type: Research article

    In a new influenza pandemic, travel data such as arrival times of cases seeded by the originating country can be regarded as a combination of the epidemic size and the mobility networks of infections connectin...

    Authors: Ka Chun Chong, Benny Chung Ying Zee and Maggie Haitian Wang

    Citation: BMC Medical Research Methodology 2017 17:31

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  7. Content type: Research article

    There is a need for improving cohort retention in longitudinal studies. Our objective was to identify cohort retention strategies and implementation approaches used in studies with high retention rates.

    Authors: Martha Abshire, Victor D. Dinglas, Maan Isabella A. Cajita, Michelle N. Eakin, Dale M. Needham and Cheryl Dennison Himmelfarb

    Citation: BMC Medical Research Methodology 2017 17:30

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  8. Content type: Research article

    In the two-stage randomised trial design, a randomly sampled subset of study participants are permitted to choose their own treatment, while the remaining participants are randomised to treatment in the usual ...

    Authors: Stephen D. Walter, Robin M. Turner, Petra Macaskill, Kirsten J. McCaffery and Les Irwig

    Citation: BMC Medical Research Methodology 2017 17:29

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  9. Content type: Research article

    Individual patient data meta-analyses (IPD-MA) are often performed using a one-stage approach-- a form of generalized linear mixed model (GLMM) for binary outcomes. We compare (i) one-stage to two-stage approa...

    Authors: Doneal Thomas, Robert Platt and Andrea Benedetti

    Citation: BMC Medical Research Methodology 2017 17:28

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  10. Content type: Research Article

    Information and theory beyond copula concepts are essential to understand the dependence relationship between several marginal covariates distributions. In a therapeutic trial data scheme, most of the time, ce...

    Authors: Charles Fontaine, Jean-Pierre Daurès and Paul Landais

    Citation: BMC Medical Research Methodology 2017 17:27

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  11. Content type: Research article

    In spite of efforts to employ risk-based strategies to increase monitoring efficiency in the academic setting, empirical evidence on their effectiveness remains sparse. This mixed-methods study aimed to evalua...

    Authors: Belinda von Niederhäusern, Annette Orleth, Sabine Schädelin, Nawal Rawi, Martin Velkopolszky, Claudia Becherer, Pascal Benkert, Priya Satalkar, Matthias Briel and Christiane Pauli-Magnus

    Citation: BMC Medical Research Methodology 2017 17:26

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  12. Content type: Research article

    Observational studies are widely used in pharmacoepidemiology. Several designs can be used, in particular self-controlled designs (case-crossover and self-controlled case series). These designs offer the advan...

    Authors: Nathalie Gault, Johann Castañeda-Sanabria, Yann De Rycke, Sylvie Guillo, Stéphanie Foulon and Florence Tubach

    Citation: BMC Medical Research Methodology 2017 17:25

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  13. Content type: Research article

    Linkage of administrative data sources often relies on probabilistic methods using a set of common identifiers (e.g. sex, date of birth, postcode). Variation in data quality on an individual or organisational ...

    Authors: Katie Harron, Gareth Hagger-Johnson, Ruth Gilbert and Harvey Goldstein

    Citation: BMC Medical Research Methodology 2017 17:23

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  14. Content type: Research article

    Multiple barriers may inhibit the adoption of clinical interventions and impede successful implementation. Use of standardised methods to prioritise barriers to target when selecting implementation interventio...

    Authors: Louise E. Craig, Leonid Churilov, Liudmyla Olenko, Dominique A. Cadilhac, Rohan Grimley, Simeon Dale, Cintia Martinez-Garduno, Elizabeth McInnes, Julie Considine, Jeremy M. Grimshaw and Sandy Middleton

    Citation: BMC Medical Research Methodology 2017 17:24

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  15. Content type: Research article

    Within epidemiological and clinical research, missing data are a common issue and often over looked in publications. When the issue of missing observations is addressed it is usually assumed that the missing d...

    Authors: M. Smuk, J. R. Carpenter and T. P. Morris

    Citation: BMC Medical Research Methodology 2017 17:21

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    The Erratum to this article has been published in BMC Medical Research Methodology 2017 17:51

  16. Content type: Research article

    The analysis of correlated binary data is commonly addressed through the use of conditional models with random effects included in the systematic component as opposed to generalized estimating equations (GEE) ...

    Authors: Jie Pu, Di Fang and Jeffrey R. Wilson

    Citation: BMC Medical Research Methodology 2017 17:20

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  17. Content type: Research article

    Participation in epidemiological studies has strongly declined in recent years. We examined the reasons for (non)participation in population-based health studies among participants and nonparticipants of a pro...

    Authors: Manas K. Akmatov, Leonhard Jentsch, Peggy Riese, Marcus May, Malik W. Ahmed, Damaris Werner, Anja Rösel, Jana Prokein, Inga Bernemann, Norman Klopp, Blair Prochnow, Thomas Illig, Christoph Schindler, Carlos A. Guzman and Frank Pessler

    Citation: BMC Medical Research Methodology 2017 17:18

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  18. Content type: Research article

    The cohort multiple randomised controlled trial (cmRCT) design provides an opportunity to incorporate the benefits of randomisation within clinical practice; thus reducing costs, integrating electronic healthc...

    Authors: Jane Candlish, Alexander Pate, Matthew Sperrin and Tjeerd van Staa

    Citation: BMC Medical Research Methodology 2017 17:17

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    The Erratum to this article has been published in BMC Medical Research Methodology 2017 17:47

  19. Content type: Research article

    In conducting population-based surveys, it is important to thoroughly examine and adjust for potential non-response bias to improve the representativeness of the sample prior to conducting analyses of the data...

    Authors: Nida H. Corry, Christianna S. Williams, Mike Battaglia, Hope Seib McMaster and Valerie A. Stander

    Citation: BMC Medical Research Methodology 2017 17:16

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  20. Content type: Research article

    The BSI-18 contains the three six-item scales somatization, depression, and anxiety as well as the Global Severity Index (GSI), including all 18 items. The BSI-18 is the latest and shortest of the multidimensi...

    Authors: Gabriele Helga Franke, Susanne Jaeger, Heide Glaesmer, Claus Barkmann, Katja Petrowski and Elmar Braehler

    Citation: BMC Medical Research Methodology 2017 17:14

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  21. Content type: Research article

    The Government of Cambodia has committed to supporting family care for vulnerable children, including homeless populations. Collecting baseline data on the numbers and characteristics of homeless adolescents w...

    Authors: Lindsay Stark, Beth L. Rubenstein, Kimchoeun Pak, Rosemary Taing, Gary Yu, Sok Kosal and Leslie Roberts

    Citation: BMC Medical Research Methodology 2017 17:13

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  22. Content type: Research article

    Data on health-related quality of life (HRQoL) is paramount for shared and evidence based decision-making. Since an overview of cervical cancer HRQoL tools and their validity appears to be lacking, we performe...

    Authors: Casper Tax, Marlie E. Steenbergen, Petra L. M. Zusterzeel, Ruud L. M. Bekkers and Maroeska M. Rovers

    Citation: BMC Medical Research Methodology 2017 17:15

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  23. Content type: Research Article

    Many questions in statistical genomics can be formulated in terms of variable selection of candidate biological factors for modeling a trait or quantity of interest. Often, in these applications, additional co...

    Authors: Jing Zhai, Chiu-Hsieh Hsu and Z. John Daye

    Citation: BMC Medical Research Methodology 2017 17:12

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  24. Content type: Research article

    Paramedics make important and increasingly complex decisions at scene about patient care. Patient safety implications of influences on decision making in the pre-hospital setting were previously under-research...

    Authors: Maxine Johnson, Rachel O’Hara, Enid Hirst, Andrew Weyman, Janette Turner, Suzanne Mason, Tom Quinn, Jane Shewan and A. Niroshan Siriwardena

    Citation: BMC Medical Research Methodology 2017 17:11

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  25. Content type: Research Article

    The attributable risk (AR) measures the proportion of disease cases that can be attributed to an exposure in the population. Several definitions and estimation methods have been proposed for survival data.

    Authors: Malamine Gassama, Jacques Bénichou, Laureen Dartois and Anne C. M. Thiébaut

    Citation: BMC Medical Research Methodology 2017 17:10

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  26. Content type: Research Article

    The risk of a disease or psychiatric disorder is frequently measured by the age-specific cumulative incidence. Cumulative incidence estimates are often derived in cohort studies with individuals recruited over...

    Authors: Stefan N. Hansen, Morten Overgaard, Per K. Andersen and Erik T. Parner

    Citation: BMC Medical Research Methodology 2017 17:7

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  27. Content type: Research article

    Many continuous item responses (CIRs) are encountered in healthcare settings, but no one uses item response theory’s (IRT) probabilistic modeling to present graphical presentations for interpreting CIR results...

    Authors: Tsair-Wei Chien, Yang Shao and Shu-Chun Kuo

    Citation: BMC Medical Research Methodology 2017 17:4

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  28. Content type: Research article

    Centralisation of thrombolysis may offer substantial benefits. The aim of this study was to assess short term costs and effects of centralisation of thrombolysis and optimised care in a decentralised system.

    Authors: Maarten M. H. Lahr, Durk-Jouke van der Zee, Gert-Jan Luijckx, Patrick C. A. J. Vroomen and Erik Buskens

    Citation: BMC Medical Research Methodology 2017 17:5

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  29. Content type: Research article

    Multiple imputation is frequently used to deal with missing data in healthcare research. Although it is known that the outcome should be included in the imputation model when imputing missing covariate values,...

    Authors: Evangelos Kontopantelis, Ian R. White, Matthew Sperrin and Iain Buchan

    Citation: BMC Medical Research Methodology 2017 17:2

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  30. Content type: Research article

    Clinical prediction models (CPMs) are increasingly deployed to support healthcare decisions but they are derived inconsistently, in part due to limited data. An emerging alternative is to aggregate existing CP...

    Authors: Glen P. Martin, Mamas A. Mamas, Niels Peek, Iain Buchan and Matthew Sperrin

    Citation: BMC Medical Research Methodology 2017 17:1

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  31. Content type: Research article

    Connected individuals (or nodes) in a network are more likely to be similar than two randomly selected nodes due to homophily and/or network influence. Distinguishing between these two influences is an importa...

    Authors: Kori Sauser Zachrison, Theodore J. Iwashyna, Achamyeleh Gebremariam, Meghan Hutchins and Joyce M Lee

    Citation: BMC Medical Research Methodology 2016 16:174

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  32. Content type: Research article

    Formative programme evaluations assess intervention implementation processes, and are seen widely as a way of unlocking the ‘black box’ of any programme in order to explore and understand why a programme funct...

    Authors: Willem Odendaal, Salla Atkins and Simon Lewin

    Citation: BMC Medical Research Methodology 2016 16:173

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  33. Content type: Research article

    Recent studies of the quality of in-hospital care have used the Quality of Interaction Schedule (QuIS) to rate interactions observed between staff and inpatients in a variety of ward conditions. The QuIS was d...

    Authors: Ines Mesa-Eguiagaray, Dankmar Böhning, Chris McLean, Peter Griffiths, Jackie Bridges and Ruth M Pickering

    Citation: BMC Medical Research Methodology 2016 16:171

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  34. Content type: Research article

    This paper describes the methodological developments of the sexual health items included in the Health Behaviour in School-aged Children (HBSC) study since their mandatory inclusion in the study in 2002. The c...

    Authors: Honor Young, András Költő, Marta Reis, Elizabeth M. Saewyc, Nathalie Moreau, Lorraine Burke, Alina Cosma, Béat Windlin, Saoirse Nic Gabhainn and Emmanuelle Godeau

    Citation: BMC Medical Research Methodology 2016 16:169

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  35. Content type: Research article

    Joint models for longitudinal and time-to-event data are commonly used to simultaneously analyse correlated data in single study cases. Synthesis of evidence from multiple studies using meta-analysis is a natu...

    Authors: Maria Sudell, Ruwanthi Kolamunnage-Dona and Catrin Tudur-Smith

    Citation: BMC Medical Research Methodology 2016 16:168

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    The Correction to this article has been published in BMC Medical Research Methodology 2018 18:33

  36. Content type: Research article

    Research reporting results of clinical trials, psychosocial or technological interventions frequently omit critical details needed to inform implementation in practice. The aim of this article is to develop an...

    Authors: Amy Streater, Aimee Spector, Elisa Aguirre, Jacki Stansfeld and Martin Orrell

    Citation: BMC Medical Research Methodology 2016 16:167

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  37. Content type: Research article

    Conventional randomized placebo-controlled study design assumes the absence of drug*placebo interaction. We hypothesized the presence of such an interaction and that conventionally estimated drug effect might ...

    Authors: Muhammad M. Hammami, Safa Hammami, Reem Al-Swayeh, Eman Al-Gaai, Faduma Abdi Farah and Sophia J. S. De Padua

    Citation: BMC Medical Research Methodology 2016 16:166

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  38. Content type: Research Article

    In an individually randomised controlled trial where the treatment is delivered by a health professional it seems likely that the effectiveness of the treatment, independent of any treatment effect, could depe...

    Authors: Laura Flight, Annabel Allison, Munyaradzi Dimairo, Ellen Lee, Laura Mandefield and Stephen J. Walters

    Citation: BMC Medical Research Methodology 2016 16:165

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  39. Content type: Research Article

    Ten events per variable (EPV) is a widely advocated minimal criterion for sample size considerations in logistic regression analysis. Of three previous simulation studies that examined this minimal EPV criteri...

    Authors: Maarten van Smeden, Joris A. H. de Groot, Karel G. M. Moons, Gary S. Collins, Douglas G. Altman, Marinus J. C. Eijkemans and Johannes B. Reitsma

    Citation: BMC Medical Research Methodology 2016 16:163

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  40. Content type: Research article

    As biobanks play an increasing role in the genomic research that will lead to precision medicine, input from diverse and large populations of patients in a variety of health care settings will be important in ...

    Authors: Maureen E. Smith, Saskia C. Sanderson, Kyle B. Brothers, Melanie F. Myers, Jennifer McCormick, Sharon Aufox, Martha J. Shrubsole, Nanibaá A. Garrison, Nathaniel D. Mercaldo, Jonathan S. Schildcrout, Ellen Wright Clayton, Armand H. Matheny Antommaria, Melissa Basford, Murray Brilliant, John J. Connolly, Stephanie M. Fullerton…

    Citation: BMC Medical Research Methodology 2016 16:162

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