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  1. Content type: Research article

    Improving participation rates in epidemiologic studies using questionnaires and biological sampling is important for the generalizability of the outcome. The aim of this study was to examine the effects of pre...

    Authors: Marie Koitsalu, Martin Eklund, Jan Adolfsson, Henrik Grönberg and Yvonne Brandberg

    Citation: BMC Medical Research Methodology 2018 18:3

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  2. Content type: Technical advance

    Many clinical trials focus on the comparison of the treatment effect between two or more groups concerning a rarely occurring event. In this situation, showing a relevant effect with an acceptable power requir...

    Authors: Ann-Kathrin Ozga, Meinhard Kieser and Geraldine Rauch

    Citation: BMC Medical Research Methodology 2018 18:2

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  3. Content type: Research article

    Hepatocellular carcinoma (HCC) has limited treatment options in patients with advanced stage disease and early detection of HCC through surveillance programs is a key component towards reducing mortality. The ...

    Authors: Nabihah Tayob, Peter Richardson, Donna L. White, Xiaoying Yu, Jessica A. Davila, Fasiha Kanwal, Ziding Feng and Hashem B. El-Serag

    Citation: BMC Medical Research Methodology 2018 18:1

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  4. Content type: Research article

    Article summaries’ information and structure may influence researchers/clinicians’ decisions to conduct deeper full-text analyses. Specifically, abstracts of systematic reviews (SRs) and meta-analyses (MA) sho...

    Authors: Francisco Gómez-García, Juan Ruano, Macarena Aguilar-Luque, Patricia Alcalde-Mellado, Jesús Gay-Mimbrera, José Luis Hernández-Romero, Juan Luis Sanz-Cabanillas, Beatriz Maestre-López, Marcelino González-Padilla, Pedro J. Carmona-Fernández, Antonio Vélez García-Nieto and Beatriz Isla-Tejera

    Citation: BMC Medical Research Methodology 2017 17:180

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  5. Content type: Research article

    Evidence shows that research abstracts are commonly inconsistent with their corresponding full reports, and may mislead readers. In this scoping review, which is part of our series on the state of reporting of...

    Authors: Guowei Li, Luciana P. F. Abbade, Ikunna Nwosu, Yanling Jin, Alvin Leenus, Muhammad Maaz, Mei Wang, Meha Bhatt, Laura Zielinski, Nitika Sanger, Bianca Bantoto, Candice Luo, Ieta Shams, Hamnah Shahid, Yaping Chang, Guangwen Sun…

    Citation: BMC Medical Research Methodology 2017 17:181

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  6. Content type: Research article

    Different confounder adjustment strategies were used to estimate odds ratios (ORs) in case-control study, i.e. how many confounders original studies adjusted and what the variables are. This secondary data ana...

    Authors: Tianyi Liu, Xiaolu Nie, Zehao Wu, Ying Zhang, Guoshuang Feng, Siyu Cai, Yaqi Lv and Xiaoxia Peng

    Citation: BMC Medical Research Methodology 2017 17:179

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  7. Content type: Research article

    Confounders can produce spurious associations between exposure and outcome in observational studies. For majority of epidemiologists, adjusting for confounders using logistic regression model is their habitual...

    Authors: Yuanyuan Yu, Hongkai Li, Xiaoru Sun, Ping Su, Tingting Wang, Yi Liu, Zhongshang Yuan, Yanxun Liu and Fuzhong Xue

    Citation: BMC Medical Research Methodology 2017 17:177

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  8. Content type: Research article

    Overuse of antibiotics contributes to the global threat of antimicrobial resistance. Antibiotic stewardship interventions address this threat by reducing the use of antibiotics in occasions or doses unlikely t...

    Authors: Patricia J. Lucas, Jenny Ingram, Niamh M. Redmond, Christie Cabral, Sophie L. Turnbull and Alastair D. Hay

    Citation: BMC Medical Research Methodology 2017 17:175

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  9. Content type: Research article

    Systematic reviews may provide less biased evidence than narrative reviews because they observe a strict methodology, similarly to primary studies. Hence, for clinical research questions, systematic reviews sh...

    Authors: Clovis Mariano Faggion Jr, Nikolaos P. Bakas and Jason Wasiak

    Citation: BMC Medical Research Methodology 2017 17:176

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  10. Content type: Research article

    Systematic reviews and meta-analyses are becoming increasingly important methods to summarize published research. Studies of ophthalmology may present additional challenges because of their potentially complex...

    Authors: Seon-Young Lee, Harkiran Sagoo, Reem Farwana, Katharine Whitehurst, Alex Fowler and Riaz Agha

    Citation: BMC Medical Research Methodology 2017 17:178

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  11. Content type: Research article

    Effectiveness of interventions in pragmatic trials may not translate directly into population impact, because of limited uptake by clinicians and/or the public. Uptake of an intervention is influenced by a num...

    Authors: Katy J. L. Bell, Amanda McCullough, Chris Del Mar and Paul Glasziou

    Citation: BMC Medical Research Methodology 2017 17:174

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  12. Content type: Research article

    Personalized healthcare relies on the identification of factors explaining why individuals respond differently to the same intervention. Analyses identifying such factors, so called predictors and moderators, ...

    Authors: Ralph van Hoorn, Marcia Tummers, Andrew Booth, Ansgar Gerhardus, Eva Rehfuess, Daniel Hind, Patrick M. Bossuyt, Vivian Welch, Thomas P. A. Debray, Martin Underwood, Pim Cuijpers, Helena Kraemer, Gert Jan van der Wilt and Wietkse Kievit

    Citation: BMC Medical Research Methodology 2017 17:173

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  13. Content type: Research article

    Prediction models and prognostic scores have been increasingly popular in both clinical practice and clinical research settings, for example to aid in risk-based decision making or control for confounding. In ...

    Authors: Sarah R. Haile, Beniamino Guerra, Joan B. Soriano and Milo A. Puhan

    Citation: BMC Medical Research Methodology 2017 17:172

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    The Correction to this article has been published in BMC Medical Research Methodology 2018 18:21

  14. Content type: Research article

    Parametric distributions based on individual patient data can be used to represent both stochastic and parameter uncertainty. Although general guidance is available on how parameter uncertainty should be accou...

    Authors: Koen Degeling, Maarten J. IJzerman, Miriam Koopman and Hendrik Koffijberg

    Citation: BMC Medical Research Methodology 2017 17:170

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  15. Content type: Research article

    Recruitment rates of older people in epidemiological studies, although relatively higher than in clinical trials, have declined in recent years. This study aimed to explore motivating factors and concerns amon...

    Authors: Alicja M. Baczynska, Sarah C. Shaw, Harnish P. Patel, Avan A. Sayer and Helen C. Roberts

    Citation: BMC Medical Research Methodology 2017 17:167

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  16. Content type: Research article

    Diagnostic tests are performed in a subset of the population who are at higher risk, resulting in undiagnosed cases among those who do not receive the test. This poses a challenge for estimating the prevalence...

    Authors: Nanhua Zhang, Si Cheng, Lilliam Ambroggio, Todd A. Florin and Maurizio Macaluso

    Citation: BMC Medical Research Methodology 2017 17:168

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  17. Content type: Research article

    Summary of findings tables in systematic reviews are highly informative but require epidemiological training to be interpreted correctly. The usage of fishbone diagrams as graphical displays could offer resear...

    Authors: Gerald Gartlehner, Marie-Therese Schultes, Viktoria Titscher, Laura C. Morgan, Georgiy V. Bobashev, Peyton Williams and Suzanne L. West

    Citation: BMC Medical Research Methodology 2017 17:169

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  18. Content type: Research article

    The variable “small for gestational age,” frequently defined as birth weight below the 10th percentile in a gestational age and sex-normalized population, is nowadays generally perceived as a more adequate mea...

    Authors: Geneviève Lefebvre and Mariia Samoilenko

    Citation: BMC Medical Research Methodology 2017 17:165

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    The Correction to this article has been published in BMC Medical Research Methodology 2018 18:17

  19. Content type: Research article

    The bias caused by drop-out is an important factor in large population-based epidemiological studies. Many studies account for it by weighting their longitudinal data, but to date there is no detailed final ap...

    Authors: Steffen C. E. Schmidt and Alexander Woll

    Citation: BMC Medical Research Methodology 2017 17:164

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  20. Content type: Research article

    Clinical studies in children are necessary yet conducting multiple visits at study centers remains challenging. The success of “care-at-home” initiatives and remote clinical trials suggests their potential to ...

    Authors: Belinda von Niederhäusern, Ramon Saccilotto, Sabine Schädelin, Victoria Ziesenitz, Pascal Benkert, Marie-Luise Decker, Anya Hammann, Julia Bielicki, Marc Pfister and Christiane Pauli-Magnus

    Citation: BMC Medical Research Methodology 2017 17:163

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  21. Content type: Research article

    As implementation science advances, the number of interventions to promote the translation of evidence into healthcare, health systems, or health policy is growing. Accordingly, classification schemes for thes...

    Authors: Susan E. Slaughter, Gabrielle L. Zimmermann, Megan Nuspl, Heather M. Hanson, Lauren Albrecht, Rosmin Esmail, Khara Sauro, Amanda S. Newton, Maoliosa Donald, Michele P. Dyson, Denise Thomson and Lisa Hartling

    Citation: BMC Medical Research Methodology 2017 17:161

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  22. Content type: Research article

    Missing data may seriously compromise inferences from randomised clinical trials, especially if missing data are not handled appropriately. The potential bias due to missing data depends on the mechanism causi...

    Authors: Janus Christian Jakobsen, Christian Gluud, Jørn Wetterslev and Per Winkel

    Citation: BMC Medical Research Methodology 2017 17:162

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  23. Content type: Technical advance

    Randomization is considered to be a key feature to protect against bias in randomized clinical trials. Randomization induces comparability with respect to known and unknown covariates, mitigates selection bias...

    Authors: Ralf-Dieter Hilgers, Diane Uschner, William F. Rosenberger and Nicole Heussen

    Citation: BMC Medical Research Methodology 2017 17:159

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Page 4 of 69