Skip to main content

Articles

Page 2 of 56

  1. Bivariate alternating recurrent event data can arise in longitudinal studies where patients with chronic diseases go through two states that occur repeatedly, e.g., care periods and break periods. However, the...

    Authors: Sandra Castro-Pearson, Aparajita Sur, Chi Hyun Lee, Chiung-Yu Huang and Xianghua Luo
    Citation: BMC Medical Research Methodology 2022 22:92
  2. Tests have false positive or false negative results, which, if not properly accounted for, may provide misleading apparent prevalence estimates based on the observed rate of positive tests and not the true dis...

    Authors: Konstantinos Pateras and Polychronis Kostoulas
    Citation: BMC Medical Research Methodology 2022 22:91
  3. Rapid Advice Guidelines (RAG) provide decision makers with guidance to respond to public health emergencies by developing evidence-based recommendations in a short period of time with a scientific and standard...

    Authors: Qi Zhou, Qinyuan Li, Janne Estill, Qi Wang, Zijun Wang, Qianling Shi, Jingyi Zhang, Xiaobo Zhang, Joseph L. Mathew, Rosalind L. Smyth, Detty Nurdiati, Zhou Fu, Hongmei Xu, Xianlan Zheng, Xiaodong Zhao, Quan Lu…
    Citation: BMC Medical Research Methodology 2022 22:89
  4. When performed in an observational setting, treatment effect modification analyses should account for all confounding, where possible. Often, such studies only consider confounding between the exposure and out...

    Authors: Antonia Mary Marsden, William G. Dixon, Graham Dunn and Richard Emsley
    Citation: BMC Medical Research Methodology 2022 22:88
  5. In case-cohort studies a random subcohort is selected from the inception cohort and acts as the sample of controls for several outcome investigations. Analysis is conducted using only the cases and the subcoho...

    Authors: Melissa Middleton, Cattram Nguyen, Margarita Moreno-Betancur, John B. Carlin and Katherine J. Lee
    Citation: BMC Medical Research Methodology 2022 22:87
  6. Group B Streptococcus (GBS) infections are a major cause of invasive disease (IGbsD) in young infants and cause miscarriage and stillbirths. Immunization of pregnant women against GBS in addition to intrapartu...

    Authors: Alane Izu, Gaurav Kwatra, Shabir A. Madhi and Fabio Rigat
    Citation: BMC Medical Research Methodology 2022 22:85
  7. Group model building (GMB) is a participatory approach whereby diverse stakeholders can share their views about a problem to create a collective understanding of a complex system. In this article we report our...

    Authors: Yanaina Chavez-Ugalde, Zoi Toumpakari, Martin White, Frank De Vocht and Russell Jago
    Citation: BMC Medical Research Methodology 2022 22:84
  8. This study shows how dynamic simulation modeling can be applied in the context of the nationwide implementation of Whole Genome Sequencing (WGS) for non-small cell lung cancer (NSCLC) to inform organizational ...

    Authors: Michiel van de Ven, Maarten IJzerman, Valesca Retèl, Wim van Harten and Hendrik Koffijberg
    Citation: BMC Medical Research Methodology 2022 22:83
  9. In the past few decades various methods have been proposed to handle missing data of clinical studies, so as to assess the robustness of primary results. Some of the methods are based on the assumption of miss...

    Authors: Shuai Wang and Haoyan Hu
    Citation: BMC Medical Research Methodology 2022 22:82
  10. Item response theory (IRT) methods for addressing differential item functioning (DIF) can detect group differences in responses to individual items (e.g., bias). IRT and DIF-detection methods have been used in...

    Authors: E. Nichols, J. A. Deal, B. K. Swenor, A. G. Abraham, N. M. Armstrong, K. Bandeen-Roche, M. C. Carlson, M. Griswold, F. R. Lin, T. H. Mosley, P. Y. Ramulu, N. S. Reed, A. R. Sharrett and A. L. Gross
    Citation: BMC Medical Research Methodology 2022 22:81
  11. The main purposes of primary care-based pharmaceutical services (PHCPS) in Brazil are to provide free access to medicines and pharmaceutical care to patients. Several obstacles hinder achieving their goals; th...

    Authors: Tatiana Chama Borges Luz, Noemia Urruth Leão Tavares, Ana Karine Sarvel de Castro, Isabela Cristina Marques, Elizabeth Moreira dos Santos and Betania Barros Cota
    Citation: BMC Medical Research Methodology 2022 22:80
  12. Deprescribing literature has been increasing rapidly. Our aim was to develop and validate search filters to identify articles on deprescribing in Medline via PubMed and in Embase via

    Authors: Thomas Morel, Jérôme Nguyen-Soenen, Wade Thompson and Jean-Pascal Fournier
    Citation: BMC Medical Research Methodology 2022 22:79
  13. Health technology assessment (HTA) brings together evidence from various disciplines while using explicit methods to assess the value of health technologies. In resource-constrained settings, there is a growin...

    Authors: Julia Bidonde, Jose Francisco Meneses-Echavez, Brian Asare, Lumbwe Chola, Mohamed Gad, Lieke Fleur Heupink and Elizabeth Fleur Peacocke
    Citation: BMC Medical Research Methodology 2022 22:78
  14. In heart data mining and machine learning, dimension reduction is needed to remove multicollinearity. Meanwhile, it has been proven to improve the interpretation of the parameter model. In addition, dimension ...

    Authors: Rezzy Eko Caraka, Rung-Ching Chen, Su-Wen Huang, Shyue-Yow Chiou, Prana Ugiana Gio and Bens Pardamean
    Citation: BMC Medical Research Methodology 2022 22:77

    The Correction to this article has been published in BMC Medical Research Methodology 2022 22:114

  15. Longitudinal studies are important to understand patterns of growth in children and limited in India. It is important to identify an approach for characterising growth trajectories to distinguish between child...

    Authors: Reka Karuppusami, Belavendra Antonisamy and Prasanna S. Premkumar
    Citation: BMC Medical Research Methodology 2022 22:76
  16. The need to mitigate the volume of unplanned emergency department (ED) presentations is a priority for health systems globally. Current evidence on the incidence and risk factors associated with unplanned ED p...

    Authors: P. H. Dufton, M. F. Gerdtz, R. Jarden and M. Krishnasamy
    Citation: BMC Medical Research Methodology 2022 22:75
  17. In 2016, international standards governing clinical research recommended that the approach to monitoring a research project should be undertaken based on risk, however it is unknown whether this approach has b...

    Authors: Renate Le Marsney, Tara Williams, Kerry Johnson, Shane George and Kristen S. Gibbons
    Citation: BMC Medical Research Methodology 2022 22:74
  18. Systematic reviews and meta-analysis of time-to-event outcomes are frequently published within the Cochrane Database of Systematic Reviews (CDSR). However, these outcomes are handled differently across meta-an...

    Authors: Theodosia Salika, Rebecca M. Turner, David Fisher, Jayne F. Tierney and Ian R. White
    Citation: BMC Medical Research Methodology 2022 22:73
  19. Systems approaches are currently being advocated and implemented to address complex challenges in Public Health. These approaches work by bringing multi-sectoral stakeholders together to develop a collective u...

    Authors: James Nobles, Jessica Wheeler, Kirsty Dunleavy-Harris, Richard Holmes, Alan Inman-Ward, Alexandra Potts, Jennifer Hall, Sabi Redwood, Russell Jago and Charlie Foster
    Citation: BMC Medical Research Methodology 2022 22:72
  20. Novel screening tests used to detect a target condition are compared against either a reference standard or other existing screening methods. However, as it is not always possible to apply the reference standa...

    Authors: Emily Day, David Eldred-Evans, A. Toby Prevost, Hashim U. Ahmed and Francesca Fiorentino
    Citation: BMC Medical Research Methodology 2022 22:70
  21. Adoption of innovations in the field of medicine is frequently hindered by a failure to recognize the condition targeted by the innovation. This is particularly true in cases where recognition requires integra...

    Authors: Meagan Bechel, Adam R. Pah, Stephen D. Persell, Curtis H. Weiss and Luís A. Nunes Amaral
    Citation: BMC Medical Research Methodology 2022 22:69
  22. Longitudinal data analysis can improve our understanding of the influences on health trajectories across the life-course. There are a variety of statistical models which can be used, and their fitting and inte...

    Authors: Ahmed Elhakeem, Rachael A. Hughes, Kate Tilling, Diana L. Cousminer, Stefan A. Jackowski, Tim J. Cole, Alex S. F. Kwong, Zheyuan Li, Struan F. A. Grant, Adam D. G. Baxter-Jones, Babette S. Zemel and Deborah A. Lawlor
    Citation: BMC Medical Research Methodology 2022 22:68
  23. Inconsistent responding is a type of invalid responding, which occurs on self-report surveys and threatens the reliability and validity of study results. This secondary analysis evaluated the utility of identi...

    Authors: Christina Schell, Alexandra Godinho and John A. Cunningham
    Citation: BMC Medical Research Methodology 2022 22:67
  24. The literature on qualitative data analysis mostly concerns analyses pertaining to an individual research question and the organization of data within that research question. Few authors have written about the...

    Authors: Joanna E. M. Sale
    Citation: BMC Medical Research Methodology 2022 22:66
  25. Recruitment into clinical trials is challenging and there is a lack of evidence on effective recruitment strategies. Personalisation of invitation letters is a potentially pragmatic and feasible way of increas...

    Authors: Ella Thiblin, Joanne Woodford, Mattias Öhman and Louise von Essen
    Citation: BMC Medical Research Methodology 2022 22:65
  26. With advances in cancer diagnosis and treatment, women with early-stage breast cancer (ESBC) are living longer, increasing the number of patients receiving post-treatment follow-up care. Best-practice survivor...

    Authors: Devesh Oberoi, Cynthia Kwok, Yong Li, Cindy Railton, Susan Horsman, Kathleen Reynolds, Anil A. Joy, Karen Marie King, Sasha Michelle Lupichuk, Michael Speca, Nicole Culos-Reed, Linda E. Carlson and Janine Giese-Davis
    Citation: BMC Medical Research Methodology 2022 22:64
  27. Online surveys have triggered a heated debate regarding their scientific validity. Many authors have adopted weighting methods to enhance the quality of online survey findings, while others did not find an adv...

    Authors: Chadia Haddad, Hala Sacre, Rony M. Zeenny, Aline Hajj, Marwan Akel, Katia Iskandar and Pascale Salameh
    Citation: BMC Medical Research Methodology 2022 22:63
  28. Recent advances in biotechnology enable the acquisition of high-dimensional data on individuals, posing challenges for prediction models which traditionally use covariates such as clinical patient characterist...

    Authors: Mariella Gregorich, Federico Melograna, Martina Sunqvist, Stefan Michiels, Kristel Van Steen and Georg Heinze
    Citation: BMC Medical Research Methodology 2022 22:62
  29. Non-random non-response bias in surveys requires time-consuming, complicated, post-survey analyses. Our goal was to see if modifying cover letter information would prevent non-random non-response bias altogeth...

    Authors: Maureen Murdoch, Barbara A. Clothier, Timothy J. Beebe, Ann K. Bangerter and Siamak Noorbaloochi
    Citation: BMC Medical Research Methodology 2022 22:61
  30. To provide empirically based guidance for substituting partner number categories in large MSM surveys with mean numbers of sexual and condomless anal intercourse (CAI) partners in a secondary analysis of surve...

    Authors: Ana Mendez-Lopez, Ford Hickson, Klaus Jansen, Nathan Lachowsky, Fiona Burns, Cinta Folch, Annie Velter, Peter Weatherburn, Ulrich Marcus, Ursula von Rüden, Massimo Mirandola, Lorenzo Gios, Jamie Frankis, David J. Brennan and Axel J. Schmidt
    Citation: BMC Medical Research Methodology 2022 22:59
  31. Causal inference has seen an increasing popularity in medical research. Estimation of causal effects from observational data allows to draw conclusions from data when randomized controlled trials cannot be con...

    Authors: Riko Kelter
    Citation: BMC Medical Research Methodology 2022 22:58
  32. The healthy context paradox, originally described with respect to school-level bullying interventions, refers to the generation of differences in mental wellbeing amongst those who continue to experience bully...

    Authors: G. J. Melendez-Torres, Emily Warren, Obioha C Ukoumunne, Russell Viner and Chris Bonell
    Citation: BMC Medical Research Methodology 2022 22:57
  33. The classical linear model is widely used in the analysis of clinical trials with continuous outcomes. However, required model assumptions are frequently not met, resulting in estimates of treatment effect tha...

    Authors: Gillian Z. Heller, Kristy P. Robledo and Ian C. Marschner
    Citation: BMC Medical Research Methodology 2022 22:56
  34. The heart rate (HR) method enables estimating oxygen uptake (V̇O2) in physical activities. However, there is a paucity in knowledge about the interchangeability of this method when applied to cycling, walking and...

    Authors: Karin Sofia Elisabeth Olsson, Hans Rosdahl and Peter Schantz
    Citation: BMC Medical Research Methodology 2022 22:55
  35. Machine learning (ML) holds the promise of becoming an essential tool for utilising the increasing amount of clinical data available for analysis and clinical decision support. However, the lack of trust in th...

    Authors: Eline Stenwig, Giampiero Salvi, Pierluigi Salvo Rossi and Nils Kristian Skjærvold
    Citation: BMC Medical Research Methodology 2022 22:53
  36. For assessing cost-effectiveness, Health Technology Assessment (HTA) organisations may use primary economic evaluations (P-HEs) or Systematic Reviews of Health Economic evaluations (SR-HEs). A prerequisite for...

    Authors: Alina Weise, Roland Brian Büchter, Dawid Pieper and Tim Mathes
    Citation: BMC Medical Research Methodology 2022 22:52
  37. The Bland-Altman plot with the limits of agreement has been widely used as an absolute index for assessing test-retest reliability or reproducibility between two measurements. We have observed that in the sett...

    Authors: Jongphil Kim and Ji-Hyun Lee
    Citation: BMC Medical Research Methodology 2022 22:51
  38. Clinical trial investigators may need to evaluate treatment effects in a specific subgroup (or subgroups) of participants in addition to reporting results of the entire study population. Such subgroups lack po...

    Authors: Rebecca M. Turner, Anna Turkova, Cecilia L. Moore, Alasdair Bamford, Moherndran Archary, Linda N. Barlow-Mosha, Mark F. Cotton, Tim R. Cressey, Elizabeth Kaudha, Abbas Lugemwa, Hermione Lyall, Hilda A. Mujuru, Veronica Mulenga, Victor Musiime, Pablo Rojo, Gareth Tudor-Williams…
    Citation: BMC Medical Research Methodology 2022 22:49
  39. The statistical evaluation of aggregation functions for trauma grades, such as the Injury Severity Score (ISS), is largely based on measurements of their Pearson product-moment correlation with mortality. Howe...

    Authors: Nassim Dehouche
    Citation: BMC Medical Research Methodology 2022 22:48
  40. Network meta-analysis estimates all relative effects between competing treatments and can produce a treatment hierarchy from the most to the least desirable option according to a health outcome. While about ha...

    Authors: Theodoros Papakonstantinou, Georgia Salanti, Dimitris Mavridis, Gerta Rücker, Guido Schwarzer and Adriani Nikolakopoulou
    Citation: BMC Medical Research Methodology 2022 22:47
  41. Two-stage least square [2SLS] and two-stage residual inclusion [2SRI] are popularly used instrumental variable (IV) methods to address medication nonadherence in pragmatic trials with point treatment settings....

    Authors: Md. Belal Hossain, Lucy Mosquera and Mohammad Ehsanul Karim
    Citation: BMC Medical Research Methodology 2022 22:46
  42. Attrition in cohort studies challenges causal inference. Although inverse probability weighting (IPW) has been proposed to handle attrition in association analyses, its relevance has been little studied in thi...

    Authors: Marie-Astrid Metten, Nathalie Costet, Luc Multigner, Jean-François Viel and Guillaume Chauvet
    Citation: BMC Medical Research Methodology 2022 22:45
  43. Prospective cohort studies are challenging to deliver, with one of the main difficulties lying in retention of participants. The need to socially distance during the COVID-19 pandemic has added to this challen...

    Authors: Emer Gates, Barnaby Hole, Samantha Hayward, Nicholas C. Chesnaye, Yvette Meuleman, Friedo W. Dekker, Marie Evans, Olof Heimburger, Claudia Torino, Gaetana Porto, Maciej Szymczak, Christiane Drechsler, Christoph Wanner, Kitty J. Jager, Paul Roderick and Fergus Caskey
    Citation: BMC Medical Research Methodology 2022 22:44
  44. Although the prevalence of hypertension is high in older adults, clinical trial recruitment is a challenge. Our main aim was to describe the HAEL Study recruitment methods and yield rates. The secondary object...

    Authors: Cíntia E. Botton, Lucas P. Santos, Bruna G. Moraes, Raíssa B. Monteiro, Maria Laura B. Gomes, Eurico N. Wilhelm, Stephanie S. Pinto and Daniel Umpierre
    Citation: BMC Medical Research Methodology 2022 22:42

Annual Journal Metrics

Peer-review Terminology

  • The following summary describes the peer review process for this journal:

    Identity transparency: Single anonymized

    Reviewer interacts with: Editor

    Review information published: Review reports. Reviewer Identities reviewer opt in. Author/reviewer communication

    More information is available here