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  1. Content type: Research article

    Decisions about which subgroup of chronic hepatitis C (CHC) patients should be treated with direct acting anti-viral agents (DAAs) have economic importance due to high drug prices. Treat-all DAA strategies for...

    Authors: Rodolfo Castro, Louise Crathorne, Hugo Perazzo, Julio Silva, Chris Cooper, Jo Varley-Campbell, Daniel Savignon Marinho, Marcela Haasova, Valdilea G. Veloso, Rob Anderson and Chris Hyde

    Citation: BMC Medical Research Methodology 2018 18:53

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  2. Content type: Research article

    Motivational Interviewing (MI), Brief Advice (BA) and Health Education (HE) are established smoking cessation induction methods for smokers with low desire to quit. Although randomized controlled trials (RCT’s...

    Authors: Majid Bani-Yaghoub, Abdellatif Elhomani and Delwyn Catley

    Citation: BMC Medical Research Methodology 2018 18:52

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  3. Content type: Research article

    Rapid response in health technology assessment is a synthesis of the best available evidence prepared in a timely manner to meet specific demands. We build a consensus among Brazilian specialists in health tec...

    Authors: Marcus Tolentino Silva, Everton Nunes da Silva and Jorge Otávio Maia Barreto

    Citation: BMC Medical Research Methodology 2018 18:51

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  4. Content type: Software

    Joint modelling of longitudinal and time-to-event outcomes has received considerable attention over recent years. Commensurate with this has been a rise in statistical software options for fitting these models...

    Authors: Graeme L. Hickey, Pete Philipson, Andrea Jorgensen and Ruwanthi Kolamunnage-Dona

    Citation: BMC Medical Research Methodology 2018 18:50

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  5. Content type: Research article

    In many studies the information of patients who are dying in the hospital is censored when examining the change in length of hospital stay (cLOS) due to hospital-acquired infections (HIs). While appropriate es...

    Authors: Shahina Rahman, Maja von Cube, Martin Schumacher and Martin Wolkewitz

    Citation: BMC Medical Research Methodology 2018 18:49

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  6. Content type: Debate

    Randomised trials with long-term follow-up can provide estimates of the long-term effects of health interventions. However, analysis of long-term outcomes in randomised trials may be complicated by problems wi...

    Authors: Robert D. Herbert, Jessica Kasza and Kari Bø

    Citation: BMC Medical Research Methodology 2018 18:48

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  7. Content type: Research article

    The successful initiation of people living with HIV/AIDS on antiretroviral therapy (ART) in South Africa has engendered challenges of poor retention in care and suboptimal adherence to medication. The adherenc...

    Authors: Ferdinand C. Mukumbang, Bruno Marchal, Sara Van Belle and Brian van Wyk

    Citation: BMC Medical Research Methodology 2018 18:47

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  8. Content type: Research article

    List randomization (LR), a survey method intended to mitigate biases related to sensitive true/false questions, has received recent attention from researchers. However, tests of its validity are limited, with ...

    Authors: Noah Haber, Guy Harling, Jessica Cohen, Tinofa Mutevedzi, Frank Tanser, Dickman Gareta, Kobus Herbst, Deenan Pillay, Till Bärnighausen and Günther Fink

    Citation: BMC Medical Research Methodology 2018 18:46

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  9. Content type: Research article

    Systematic reviews and meta-analyses of observational studies are frequently performed, but no widely accepted guidance is available at present. We performed a systematic scoping review of published methodolog...

    Authors: Monika Mueller, Maddalena D’Addario, Matthias Egger, Myriam Cevallos, Olaf Dekkers, Catrina Mugglin and Pippa Scott

    Citation: BMC Medical Research Methodology 2018 18:44

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  10. Content type: Research article

    Researchers and funders should consider the statistical power of planned Individual Participant Data (IPD) meta-analysis projects, as they are often time-consuming and costly. We propose simulation-based power...

    Authors: Joie Ensor, Danielle L. Burke, Kym I. E. Snell, Karla Hemming and Richard D. Riley

    Citation: BMC Medical Research Methodology 2018 18:41

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  11. Content type: Research article

    Information on causes of death (COD) is crucial for measuring the health outcomes of populations and progress towards the Sustainable Development Goals. In many countries such as Vietnam where the civil regist...

    Authors: Hong Thi Tran, Hoa Phuong Nguyen, Sue M. Walker, Peter S. Hill and Chalapati Rao

    Citation: BMC Medical Research Methodology 2018 18:43

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  12. Content type: Research article

    Recent methodologic evidence suggests that lack of blinding in randomized trials can result in under- or overestimation of the treatment effect size. The objective of this study is to quantify the extent of bi...

    Authors: Humam Saltaji, Susan Armijo-Olivo, Greta G. Cummings, Maryam Amin, Bruno R. da Costa and Carlos Flores-Mir

    Citation: BMC Medical Research Methodology 2018 18:42

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  13. Content type: Research article

    Accurate smoking status is key for research purposes, but can be costly and difficult to measure. Within the Veteran’s Health Administration (VA), smoking status is recorded as part of routine care as “health ...

    Authors: Anne C. Melzer, Erika A. Pinsker, Barbara Clothier, Siamak Noorbaloochi, Diana J. Burgess, Elisheva R. Danan and Steven S. Fu

    Citation: BMC Medical Research Methodology 2018 18:39

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  14. Content type: Research article

    For an intervention to be considered evidence-based, findings need to be replicated. When this is done in new contexts (e.g., a new country), adaptations may be needed. Yet, we know little about how researcher...

    Authors: Ulrica von Thiele Schwarz, Ulrika Förberg, Knut Sundell and Henna Hasson

    Citation: BMC Medical Research Methodology 2018 18:36

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  15. Content type: Research article

    Systematic reviews (SRs) in the field of neuropathic pain (NeuP) are increasingly important for decision-making. However, methodological flaws in SRs can reduce the validity of conclusions. Hence, it is import...

    Authors: Svjetlana Dosenovic, Antonia Jelicic Kadic, Katarina Vucic, Nikolina Markovina, Dawid Pieper and Livia Puljak

    Citation: BMC Medical Research Methodology 2018 18:37

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  16. Content type: Research article

    Certain cancer case ascertainment methods used in Quebec and elsewhere are known to underestimate the burden of cancer, particularly for some subgroups. Algorithms using claims data are a low-cost option to im...

    Authors: Mamadou Diop, Erin C. Strumpf and Geetanjali D. Datta

    Citation: BMC Medical Research Methodology 2018 18:38

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  17. Content type: Debate

    When discussing results medical research articles often tear substantive and statistical (methodical) contributions apart, just as if both were independent. Consequently, reasoning on bias tends to be vague, u...

    Authors: Michael Höfler, John Venz, Sebastian Trautmann and Robert Miller

    Citation: BMC Medical Research Methodology 2018 18:34

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  18. Content type: Correction

    Following publication of the original article [1] the authors reported that reference 15 (Cella et al.) had been incorrectly replaced with a duplicate of Brombin et al. during publication.

    Authors: Maria Sudell, Ruwanthi Kolamunnage-Dona and Catrin Tudur-Smith

    Citation: BMC Medical Research Methodology 2018 18:33

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    The original article was published in BMC Medical Research Methodology 2016 16:168

  19. Content type: Research article

    Sample size planning for longitudinal data is crucial when designing mediation studies because sufficient statistical power is not only required in grant applications and peer-reviewed publications, but is ess...

    Authors: Haitao Pan, Suyu Liu, Danmin Miao and Ying Yuan

    Citation: BMC Medical Research Methodology 2018 18:32

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  20. Content type: Research article

    Many biological variables sampled from human subjects show a diurnal pattern, which poses special demands on the techniques used to analyze such data. Furthermore, most biological variables belong to nonlinear...

    Authors: Roelof B. Toonen, Klaas J. Wardenaar, Elisabeth H. Bos, Sonja L. van Ockenburg and Peter de Jonge

    Citation: BMC Medical Research Methodology 2018 18:31

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  21. Content type: Research article

    Increasing numbers of systematic reviews (SRs) on total knee arthroplasty (TKA) and total hip arthroplasty (THA) have been published in recent years, but their quality has been unclear. The purpose of this stu...

    Authors: Xinyu Wu, Huan Sun, Xiaoqin Zhou, Ji Wang and Jing Li

    Citation: BMC Medical Research Methodology 2018 18:30

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  22. Content type: Research article

    Measures of mental well-being and positive mental health (PMH) have been largely developed and used in Western populations, however, data on representative Asian communities are lacking. Using data from a popu...

    Authors: Janhavi Ajit Vaingankar, Mythily Subramaniam, Linda Wei Lin Tan, Edimansyah Abdin, Wei Yen Lim, Hwee Lin Wee, Siow Ann Chong and Rob Martinus van Dam

    Citation: BMC Medical Research Methodology 2018 18:29

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